Alpha Crystallin B Chain

Alpha B chain crystallins (αBC) can be induced by heat shock, ischemia, and oxidation, and are members of the small heat shock protein (sHSP also known as the HSP20) family. [6] [11] They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead, they bind improperly folded proteins to prevent protein aggregation. Disease description An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Alpha-crystallin B chain. Gene. CRYAB. Organism. Bos taurus (Bovine) Status. Reviewed-Annotation score: -Experimental evidence at protein level i. Function i. May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. . Western Blot analysis: 0.05 µg/mL of this antibody detected Alpha-crystallin B chain in 10 µg of human kidney and calf kidney tissue lysate. Research Category Neuroscience Research Sub Category Developmental Neuroscience Target description ~20 kDa observed. Uncharacterized bands at ~37 and 43 kDa may be observed in some cell lyates. Alpha-crystallin B chain, ACD domain (IPR037882) Description This entry represents the alpha-crystallin domain (ACD) found in the small heat shock protein (sHsp) alphaB-crystallin (HspB5, 20kDa). 魚 料理 の 店 鮮魚 まる ふく. alpha-crystallin B chain, alpha(B)-crystallin, crystallin, alpha 2, heat shock protein CryAB, heat shock protein HspB5. GeneRIFs: Gene References Into Functions. This study demonstrated that HspB5 mRNA localization in myelin-enriched white and gray matter CRYAB (Crystallin Alpha B) is a Protein Coding gene. Diseases associated with CRYAB include Myopathy, Myofibrillar, 2 and Cataract 16, Multiple Types.Among its related pathways are Longevity regulating pathway and Protein processing in endoplasmic reticulum.Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and microtubule binding. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the . Alpha-crystallin occurs as large aggregates, comprising two types of related subunits (A and B) that are highly similar to the small (15-30kDa) heat shock proteins (), particularly in their C-terminal halves.The relationship between these families is one of classic gene duplication and divergence, from the small HSP family, allowing adaptation to novel functions. alpha-Crystallin B Chain Alfakrystallin B-kedja Engelsk definition. One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY.Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME . "alpha-Crystallin B Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Anti-alpha B-crystallin Antibody | Sigma-Aldrich

Western Blot analysis: 0.05 µg/mL of this antibody detected Alpha-crystallin B chain in 10 µg of human kidney and calf kidney tissue lysate. Research Category Neuroscience Research Sub Category Developmental Neuroscience Target description ~20 kDa observed. Uncharacterized bands at ~37 and 43 kDa may be observed in some cell lyates. M.F. Ahmad, B. Raman, T. Ramakrishna, C.M. RaoEffect of phosphorylation on alpha B-crystallin: differences in stability, subunit exchange and chaperone activity of homo and mixed oligomers of alpha B-crystallin and its phosphorylation-mimicking mutant Elisa kit to Alpha crystallin chain product information; Elisa kit to Alpha crystallin chain is available 4 times from supplier Cusabio at Gentaur.com shop

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Cryab crystallin, alpha B [ (house mouse)]

alpha-crystallin B chain, alpha(B)-crystallin, crystallin, alpha 2, heat shock protein CryAB, heat shock protein HspB5. GeneRIFs: Gene References Into Functions. This study demonstrated that HspB5 mRNA localization in myelin-enriched white and gray matter It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance. Alpha-B crystallin has been linked to Alexander's disease where it accumulates in brain cells of those afflicted. "alpha-Crystallin A Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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What does ALPHA-CRYSTALLIN B CHAIN stand for?

Looking for the definition of ALPHA-CRYSTALLIN B CHAIN? Find out what is the full meaning of ALPHA-CRYSTALLIN B CHAIN on Abbreviations.com! The Web's largest and most authoritative acronyms and abbreviations resource. Crystallins, alpha A Chain (n.). 1. One of the subunits of alpha-crystallinsUnlike ALPHA-CRYSTALLIN B CHAIN the expression of ALPHA-CRYSTALLIN A CHAIN is limited primarily to the lens (LENS, CRYSTALLINE).

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Anti-Alpha B Crystallin antibody [1B6.1-3G4] (ab13496) | Abcam

ab13496 staining Alpha B Crystallin in mouse brain tissue by Immunohistochemistry (free floating sections). Samples were incubated with the primary antibody at a 1/500 dilution for 16 hours at 4°C. A goat anti-mouse IgG conjugated to Alexa Fluor®594 was used as secondary antibody at a 1/10000 dilution. Alias CRYαB (Crystallin Alpha B) ELISA Kit, CRYAB ELISA Kit, CRYA2 ELISA Kit, CTPP2 ELISA Kit, HSPB5 ELISA Kit, alpha B crystallin ELISA Kit, alpha (B) -crystallin ELISA Kit, alpha-crystallin B chain ELISA Kit, alpha crystallin B chain ELISA Kit, Heat shock protein beta-5 ELISA Kit, heat-shock 20 kD like-protein ELISA Kit, Renal carcinoma antigen NY-REN-27 ELISA Kit, Rosenthal fiber component ...

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1409 - Gene ResultCRYAA crystallin alpha A [ (human)]

The loss of interactions between alpha A-crystallin N-terminal mutants and alpha B-crystallin signifies quaternary structural alterations due to mutation in the arginine residues. CpG islands hypermethylation of alphaA-crystallin gene may be involved in nuclear cataract formation after pars plana vitrectomy. Definition of alpha-crystallin a chain in the Definitions.net dictionary. Meaning of alpha-crystallin a chain. What does alpha-crystallin a chain mean? Information and translations of alpha-crystallin a chain in the most comprehensive dictionary definitions resource on the web.

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1410 - Gene ResultCRYAB crystallin alpha B [ (human)]

Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the ... Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Alpha-crystallin B chain, was expressed in the hosts and tags indicated. Please select your host/tag option, above. NX_P02489 - CRYAA - Alpha-crystallin A chain - Function. Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.

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alpha-Crystallin B Chain | Colorado PROFILES

"alpha-Crystallin B Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. alpha-Crystallin B Chain Subject Areas on Research ...

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alpha-Crystallin B Chain - Karolinska Institutet

alpha-Crystallin B Chain Alfakrystallin B-kedja Engelsk definition. One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY.Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME ... Alpha-Crystallin B Chain information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues.

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alpha-Crystallin B Chain | Profiles RNS

"alpha-Crystallin B Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. "alpha-Crystallin A Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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CRYAB - Wikipedia

Alpha B chain crystallins (αBC) can be induced by heat shock, ischemia, and oxidation, and are members of the small heat shock protein (sHSP also known as the HSP20) family. [6] [11] They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead, they bind improperly folded proteins to prevent protein aggregation. Anti-alpha B-crystallin Antibody, clone CPTC-CRYAB-1; Synonym: crystallin, alpha B, alpha(B)-crystallin, heat-shock 20 kD like-protein, alpha-crystallin B chain, Rosenthal fiber component, alpha crystallin B chain, Renal carcinoma antigen NY-REN-27, alpha B crystallin, Heat shock protein beta-5, Alpha(B)-crystallin; find Sigma-Aldrich-MABN31 MSDS, related peer-reviewed papers, technical ... CRYAB A gene on chromosome 11q22.3-q23.1 that encodes alpha crystallin B, a protein induced by heat shock that belongs to the small heat shock protein (sHSP, or HSP20) family.

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Alpha-crystallin B chain, ACD domain (IPR037882 ...

Alpha-crystallin B chain, ACD domain (IPR037882) Description This entry represents the alpha-crystallin domain (ACD) found in the small heat shock protein (sHsp) alphaB-crystallin (HspB5, 20kDa). A list of lyrics, artists and songs that contain the term "alpha-crystallin b chain" - from the Lyrics.com website. Anti-alpha B-crystallin Antibody, clone aB1788G7G6 Anti-alpha B-crystallin, clone aB1788G7G6, Cat. No. MABN2552, is a highly specific mouse monoclonal antibody that targets Alpha-crystallin B chain and has been tested for use in ELISA, Immunofluorescence, Immunohistochemistry, Inhibition Assay, and Western Blotting. - Find MSDS or SDS, a COA, data sheets and more information.

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CRYAB - Alpha-crystallin B chain - Function

NX_P02511 - CRYAB - Alpha-crystallin B chain - Function. May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Crystallin Alpha B is also known as Alpha(B)-crystallin, Alpha-crystallin B chain, AlphaB Crystallin/CRYAB, CRYA2, CRYAB, CRYalphaB, Heat shock protein beta-5, HspB5, p23, Rosenthal fiber component . Open Advanced Filter 12 Applications, 15 Species currently selected. OR (match all ...

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alpha crystallin b chain : définition de alpha crystallin ...

alpha-Crystallin B Chain (n.) 1. One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE. The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence ...

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What does alpha-crystallin b chain mean? - definitions

Definition of alpha-crystallin b chain in the Definitions.net dictionary. Meaning of alpha-crystallin b chain. What does alpha-crystallin b chain mean? Information and translations of alpha-crystallin b chain in the most comprehensive dictionary definitions resource on the web. CRYAB A gene on chromosome 11q22.3-q23.1 that encodes alpha crystallin B, a protein induced by heat shock that belongs to the small heat shock protein (sHSP, or HSP20) family.

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CRYAB Gene - GeneCards | CRYAB Protein | CRYAB Antibody

CRYAB (Crystallin Alpha B) is a Protein Coding gene. Diseases associated with CRYAB include Myopathy, Myofibrillar, 2 and Cataract 16, Multiple Types.Among its related pathways are Longevity regulating pathway and Protein processing in endoplasmic reticulum.Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and microtubule binding. "alpha-Crystallin A Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Mouse monoclonal Alpha B Crystallin antibody [6D11]. Validated in WB, IP, IHC, Flow Cyt, ICC/IF and tested in Rat, Human, Monkey. Immunogen corresponding to recombinant full length protein.

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CRYAB - Alpha-crystallin B chain - Bos taurus (Bovine ...

Alpha-crystallin B chain. Gene. CRYAB. Organism. Bos taurus (Bovine) Status. Reviewed-Annotation score: -Experimental evidence at protein level i. Function i. May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. ... fnab00325 Rabbit Human Mouse Rat ELISA IHC IP WB crystallin, alpha B Alpha B Crystallin, Alpha crystallin B chain, Alpha(B) crystallin, CRYA2, CRYAB, crystallin, alpha B, CTPP2, Heat shock protein beta 5, HSPB5, Rosenthal fiber component P02511 Mouse Alpha-crystallin B chain (Cryab) ELISA Kit can measure Mouse Alpha-crystallin B chain in serum, blood, plasma, cell culture supernatant and other related supernatants and tissues. The cookie settings on this website are set to 'allow all cookies' to give you the very best experience.

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Medical vocabulary: What does alpha-Crystallin B Chain mean

What does alpha-Crystallin B Chain mean in English? Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. Alternative ...

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Crystallin - Wikipedia

Alpha-crystallin occurs as large aggregates, comprising two types of related subunits (A and B) that are highly similar to the small (15-30kDa) heat shock proteins (), particularly in their C-terminal halves.The relationship between these families is one of classic gene duplication and divergence, from the small HSP family, allowing adaptation to novel functions. Description The Rabbit Alpha-Crystallin B Chain (CRYAB) ELISA Kit is a α- or alpha protein sometimes glycoprotein present in blood. Properties E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays ... motifs/domains: N-terminal domain involved in multiple interactions that enable the formation of various oligomers and binding to denatured proteins, thereby enabling chaperone-like activities, and the hydrophobic region (AAs 41–58) of the N-terminal domain is involved in the recognition of denatured protein

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CRYAB - Alpha-crystallin B chain - Homo sapiens (Human ...

Disease description An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Alpha Crystallin. α-Crystallin is an aggregate of two polypeptides, αA and αB, which are small heat shock proteins that prevent ultraviolet (A and B) induced protein aggregation [93,94]. Antonyms for alpha-crystallin b chain at Synonyms.com with free online thesaurus, synonyms, definitions and translations.

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alpha-Crystallin B Chain | Harvard Catalyst Profiles ...

"alpha-Crystallin B Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Chicken Alpha-crystallin B chain (CRYAB) ELISA Kit can measure Chicken Alpha-crystallin B chain in serum, blood, plasma, cell culture supernatant and other related supernatants and tissues. The cookie settings on this website are set to 'allow all cookies' to give you the very best experience.

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